FFECTS OF EXPERIMENTAL Trypanosoma evansi INFECTION ON PREGNANCY AND SOME PREGNANCY ASSOCIATED SERUM FACTORS INYANKASA EWES

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dc.contributor.authorADEYEYE, Adewale Ayodeji
dc.date.accessioned2016-04-06T10:58:53Z
dc.date.available2016-04-06T10:58:53Z
dc.date.issued2015-08
dc.descriptionA DISSERTATION SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILLMENT OF THEREQUIREMENTS FOR THE AWARD OF A DOCTOR OF PHILOSOPHY IN THERIOGENOLOGY DEPARTMENT OF THERIOGENOLOGY AND PRODUCTION AHMADU BELLO UNIVERSITY, ZARIAen_US
dc.description.abstractTwenty pregnantYankasa ewes which were oestrus synchronized and mated naturally were assigned into 3 groups according to their weights, to determine the effect of Trypanosomaevansiinfection on pregnancy and some pregnancy associated serum factors. Groups A and B comprising7 ewes each were infected with approximately 1.0 x106 of T. evansi per ewe through venipunctureat the second and third trimesters of pregnancy, respectively. Group C comprising 6 ewes served as uninfected control. Parasitaemia was detected between days 11 and 25 post-infection (pi) and between days 13 and 22 pi in groups A and B, respectively and fluctuated thereafter, while ewes in group C remained aparasitaemic throughout the study. There was slight pyrexia in the infected groups (A and B) but absent in group C. The mean body weight changes, glucose concentration and packed cell volume (PCV) of ewes in group A were not significantly(p>0.05) different from those in group C throughout the study. There was also no significant (p>0.05) difference in mean glucose concentration between group B and C. However, in group B, the mean body weight was significantly(p<0.05) lower compared to group C at week 2 and from week 4 pi till the end of the study; the PCV also significantly(p<0.05) decreased but at weeks 4 and 6 pi only. Leukopenia was observed in group A at week 1 pi, followed by leukocytosis at week 4 pi and then leukopenia at week 7 pi. Ewes in group B also showed leukopenia but at week 3 pi and thiscoincided with peak parasitaemia. The mean plasma protein (PPr) of ewes in group A was significantly(p<0.05)increasedcompared to those of group C at weeks 7and 11 pi, thereafter till the end of the study. On the contrary, the PPr of ewes in group B decreased significantly(p<0.05) compared to group C at weeks 2 and 6 pi.The mean progesterone (P4) and pregnancy associated glycoprotein (PAG) levels of ewesen_US
dc.identifier.urihttp://hdl.handle.net/123456789/7617
dc.language.isoenen_US
dc.subjectFFECTS,en_US
dc.subjectEXPERIMENTAL Trypanosoma evansi INFECTION,en_US
dc.subjectPREGNANCY,en_US
dc.subjectPREGNANCY ASSOCIATED SERUM,en_US
dc.subjectFACTORS INYANKASA EWES,en_US
dc.titleFFECTS OF EXPERIMENTAL Trypanosoma evansi INFECTION ON PREGNANCY AND SOME PREGNANCY ASSOCIATED SERUM FACTORS INYANKASA EWESen_US
dc.typeThesisen_US
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