HUMAN RESPIRATORY SYNCYTIAL VIRUS INFECTION AMONG CHILDREN 1-5 YEARS IN ZARIA, KADUNA STATE, NIGERIA

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dc.contributor.authorALIYU, AISHATU MOHAMMED
dc.date.accessioned2014-02-26T10:59:22Z
dc.date.available2014-02-26T10:59:22Z
dc.date.issued2009-03
dc.descriptionA THESIS SUBMITTED TO THE POSTGRADUATE SCHOOL, AHMADU BELLO UNIVERSITY, ZARIA NIGERIA IN PARTIAL FULFILLMENT FOR THE AWARD OF MASTERS OF SCIENCE IN MICROBIOLOGY DEPARTMENT OF MICROBIOLOGY AHMADU BELLO UNIVERSITY, ZARIA NIGERIA MARCH 2009en_US
dc.description.abstractSerological survey was carried out among children in Zaria to determine the level of Respiratory syncytial virus IgG antibodies. Blood samples of children aged 12 –60 months were collected in three out patient clinics of Ahmadu Bello University Teaching Hospital Zaria. Respiratory syncytial virus IgG antibody level was measured using commercial ELISA kit obtained from DEMEDITEC DIAGNOSTIC GmbH Germany. Three hundred and eighty four blood samples, were collected how ever 379 were analyzed due to lyses of some. Of the 379 blood samples analyzed, 353 (93.1%) were seropositive for Respiratory Syncytial Virus. There was female predominance, with 178 (94.2%) being positive compared to males 175(92.1%) but the difference was not statistically significant (P value >0.05). However, statistical association was observed between age and seropositivity (P value<0.05). The seroprevalence was highest (98.7%) in age group 49-60 months and lowest in age group 0-12 months (78.6%). There was no association between the presence of cough, catarrh and/or running nose with seropositivity (P value >0.05). The result also shows no association with the presence of sickle cell disease and parental smoking with seropositivity (p value >0.05). This study has revealed that children ages 1-5 years have very high prevalence of RSV infection in Zaria, and therefore, highlighting the need for the younger age group to be targeted for prevention programme against RSV infectionen_US
dc.identifier.urihttp://hdl.handle.net/123456789/2771
dc.language.isoenen_US
dc.subjectHUMANen_US
dc.subjectRESPIRATORYen_US
dc.subjectSYNCYTIALen_US
dc.subjectVIRUSen_US
dc.subjectINFECTIONen_US
dc.subjectAMONGen_US
dc.subjectCHILDREN 1-5 YEARSen_US
dc.subjectZARIA,en_US
dc.subjectKADUNAen_US
dc.subjectNIGERIAen_US
dc.titleHUMAN RESPIRATORY SYNCYTIAL VIRUS INFECTION AMONG CHILDREN 1-5 YEARS IN ZARIA, KADUNA STATE, NIGERIAen_US
dc.typeThesisen_US
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