KINETICS AND MECHANISMS OF OXIDATION OF SOME ALKALOIDS (CAFFEINE, IMIDAZOLE, THEOBROMINE AND THEOPHYLLINE) BY PERMANGANATE ION IN AQUEOUS ACIDIC MEDIUM

Simple item page
dc.contributor.authorJONES, FRANK
dc.date.accessioned2014-02-10T10:26:14Z
dc.date.available2014-02-10T10:26:14Z
dc.date.issued2012-10
dc.descriptionA THESIS SUBMITTED TO THE POSTGRADUATE SCHOOL, AHMADU BELLO UNIVERSITY, ZARIA NIGERIA IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE IN INORGANIC CHEMISTRYen_US
dc.description.abstractThe kinetics of the redox reactions of caffeine (CAF), imidazole (IDZ), theobromine (TB) and theophylline(TP) have been studied in aqueous acid medium. Stoichiometries of the reactions, determined by the mole ratio method were observed to be 1:1(CAF- MnO􀬸 􀬿and TP − MnO􀬸 􀬿) and 1:2 (IDZ- MnO􀬸 􀬿and TB- MnO􀬸 􀬿) systems respectively. The rate of the reactions showed two parallel acid pathways, the acid dependent and the acid independent pathway for all the systems studied. The kinetic results showed first order dependence with respect to permanganate ion and reductants (CAF, IDZ, TB, TP) concentrations respectively. The reactions obey second order kinetics with the following general rate laws. – d[MnO4 –]/dt =k2[MnO􀬸 􀬿][S] where (S = CAF, IDZ, TB or TP) with k2 (CAF) = 4.0 × 10–2 ± 0.02mol dm–3, k2 (IDZ) = 9.1 × 10–2 ± 0.1 mol dm–3, k2 (TB) = 9.2 × 10–2 ± 0.02 mol dm–3 and k2 (TP) = 5.4 × 10–1 ± 0.2 mol dm–3 Spectroscopic studies and Michaelis-Menten plots showed no evidence of the formation of intermediate complex in all the systems. Free radical were also not observed. Added ions (HCOO─, CO3 2 ─Mg2+ and Ca2+) were observed to catalyze the reactions.The outer-sphere mechanism is proposed for these reactions .en_US
dc.identifier.urihttp://hdl.handle.net/123456789/848
dc.language.isoenen_US
dc.subjectKINETICSen_US
dc.subjectMECHANISMSen_US
dc.subjectOXIDATIONen_US
dc.subjectALKALOIDSen_US
dc.titleKINETICS AND MECHANISMS OF OXIDATION OF SOME ALKALOIDS (CAFFEINE, IMIDAZOLE, THEOBROMINE AND THEOPHYLLINE) BY PERMANGANATE ION IN AQUEOUS ACIDIC MEDIUMen_US
dc.typeThesisen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
KINETICS AND MECHANISMS OF OXIDATION OF SOME ALKALOIDS (CAFFEINE, IMIDAZOLE, THEOBROMINE AND THEOPHYLLINE) BY PERMANGANATE ION IN AQUEOUS ACIDIC MEDIUM.pdf
Size:
7.4 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.58 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
SCIENCE