PHYTOCHEMICAL INVESTIGATIONS ON STRIGA SENEGALENSIS BENTH (Family- Scrophulariaceae)

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dc.contributor.authorMarting, Zechariah Garba
dc.date.accessioned2014-02-05T12:15:12Z
dc.date.available2014-02-05T12:15:12Z
dc.date.issued1989-08
dc.descriptionDepartment of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaira, Nigeria. In partial fulfillment of the requirements for the award of Master of Science Degree in Pharmaceutical Chemistry (Pharmaceutical and Medicinal Chemistry).en_US
dc.description.abstractStriga Senegalensis Benth is among the worst weeds of the world, but locally, it is an ethnomedicinal plant. Its antifertility and abortifacient activities have been published however little on its Chemistry is known. ST-1 , an isolate from its (the plant) ethylacetate exract was physically (spectroscopic methods) and chemically examined. The information obtained led to the proposed structure: 2- Carbonamide-6-hydroxy-9H-carbazole ( a carbazole alkaloid). The ethanolic extract of the plant had marked effects on the isolated heart artria and ileum of the rat and rabbit respectively . Its mechanism of action on the uterus appeared to be that of interfering with calcium ingress and / or calcium release from intracellular store.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/344
dc.language.isoenen_US
dc.subjectPHYTOCHEMICAL,en_US
dc.subjectINVESTIGATIONS,en_US
dc.subjectSTRIGA,en_US
dc.subjectSENEGALENSIS,en_US
dc.subjectBENTH,en_US
dc.subjectFamily,en_US
dc.subjectScrophulariaceaeen_US
dc.titlePHYTOCHEMICAL INVESTIGATIONS ON STRIGA SENEGALENSIS BENTH (Family- Scrophulariaceae)en_US
dc.typeThesisen_US
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