STUDIES IN THE CATION- INDUCED CYCLISATION OF OLEFINS

No Thumbnail Available
Date
1979-02-05
Authors
AMUPITAN, J. 0.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Chapter 1 consists of a review of the role of squalene oxide in the biogenesis of triterpenoids and steroids via lanosterol. A number of non-enzymic methods of inducing such cyclisations under various conditions is also presented with greater emphasis on the more successful techniques. Chapter 2 starts with a review of the classical route to the synthesis of 2-alkylcyclohexenones via alkylation of Hagemann's ester. This is followed by a series of reactions carried out by the author leading to a novel synthetic route to the 2-alkylcyclohexenones, which is shown to be much better than the former route. A review of the Lewis acid induced cyclisation of epoxyolefins already carried out by a number of workers in our Laboratories is also presented followed by the cyclisations of epoxyolefins and alpha, Beta -unsaturated ketones carried out by the author. It is hereby demonstrated that formation of bi-, tri- and tetra- cyclic systems are feasible under suitable conditions. Chapter 3 consists of the experimental work of reactions mentioned in Chapter 2.
Description
A Thesis entitled STUDIES IN THE CATION- INDUCED CYCLISATION OF OLEFINS presented by J. 0. AMUPITAN, M.Sc. in part fulfilment of the requirements of The Victoria University of Manchester for the degree of DOCTOR OF PHILOSOPHY
Keywords
STUDIES, STUDIES, CYCLISATION, OLEFINS
Citation
Collections