STUDIES IN THE CATION- INDUCED CYCLISATION OF OLEFINS
STUDIES IN THE CATION- INDUCED CYCLISATION OF OLEFINS
No Thumbnail Available
Date
1979-02-05
Authors
AMUPITAN, J. 0.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Chapter 1 consists of a review of the role of squalene oxide in
the biogenesis of triterpenoids and steroids via lanosterol. A number
of non-enzymic methods of inducing such cyclisations under various conditions
is also presented with greater emphasis on the more successful
techniques.
Chapter 2 starts with a review of the classical route to the
synthesis of 2-alkylcyclohexenones via alkylation of Hagemann's ester.
This is followed by a series of reactions carried out by the author
leading to a novel synthetic route to the 2-alkylcyclohexenones, which
is shown to be much better than the former route. A review of the
Lewis acid induced cyclisation of epoxyolefins already carried out by
a number of workers in our Laboratories is also presented followed by
the cyclisations of epoxyolefins and alpha, Beta -unsaturated ketones carried
out by the author. It is hereby demonstrated that formation of bi-,
tri- and tetra- cyclic systems are feasible under suitable conditions.
Chapter 3 consists of the experimental work of reactions mentioned
in Chapter 2.
Description
A Thesis entitled
STUDIES IN THE CATION- INDUCED CYCLISATION OF OLEFINS
presented by
J. 0. AMUPITAN, M.Sc.
in part fulfilment of the requirements of
The Victoria University of Manchester
for the degree of DOCTOR OF PHILOSOPHY
Keywords
STUDIES, STUDIES, CYCLISATION, OLEFINS