EFFECT OF LACTOSE- IN- SALINE INFUSION ON SOME SERUM BIOCHEMICAL PARAMETERS OF CATTLE INFECTED WITH TRYPANOSOMA V1VAX
EFFECT OF LACTOSE- IN- SALINE INFUSION ON SOME SERUM BIOCHEMICAL PARAMETERS OF CATTLE INFECTED WITH TRYPANOSOMA V1VAX
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Date
1998-04
Authors
KADIMA, KWEM BAKAU
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Abstract
Thirty six (36) apparently healthy Zebu cattle in Zaria, were assayed for some serum
biochemical parameters. The mean serum concentrations were as follows Na+ ,
140.03 ± 5.54 (mMol/1); C1-, 98.67 ± 2.23(mMol/l); K+,4.36 ± 0.40 (mMol/1);
HCO,, 23.69± 2.69 (mMol/1); Glucose, 4.64± 5.20 (mMol/1); Bilirubin, 6.94± 3.22
(mMol/1); BUN, 5.66 ±2.11 (mMol/1); AST 46.96 ±11.25 (IU/1) and Albumin, 26.6
±3.16 (g/1). The standard deviations were within explanable limits and the mean
serum concentrations of these parameters reflects that the animals under investigation
were apparently healthy.
A set of four 4 (Group B) young zebu cattle were infected with a Zaria strain
Trypanosoma vivax. The serum biochemical parameters was investigated, serum Na+
and CI- levels significantly (p<0.05) increased following decreasing parasitaemia on
days, 6, 7 and 8 post infection (p.i), while the greatest drop was on day 9 p.i to a
point of hyponatremia and hypochloremia. Serum K+values significantly (p<0.05)
decreased during this period, while serum HCO'3 showed significant (p<0.005)
intermittent increases at the same period indicating a possible metabolic disturbance
and / or kidney's inability to control the electrolyte changes. Serum bilirubin and
Albumin levels significantly (p<0.05) increased following increasing parasitemia due
to erythroclensis taking place and catabolic breakdown of proteins following fever of
parasitemia. Serum glucose parasitemia significantly increased following decreasing
parasitemia indicating that there is a relationship between glucose levels and
parasitemia.
Description
BEING A THESIS SUBMITTED TO THE POSTGRADUATE SCHOOL,
AHMADU BELLO UNIVERSITY ZARIA IN PARTIAL FULFILLMENT
OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE
IN VETERINARY MEDICINE
DEPARTMENT OF VETERINARY PATHOLOGY & MICROBIOLOGY
FACULTY OF VETERINARY MEDICINE
AHMADU BELLO UNIVERSITY
ZARIA, NIGERIA
APRIL, 1998
Keywords
LACTOSE- IN- SALINE,, SERUM BIOCHEMICAL,, PARAMETERS,, CATTLE,, INFECTED,, TRYPANOSOMA V1VAX