SEROPREVALENCE AND MOLECULAR DETECTION OF RUBELLA VIRUS AMONG WOMEN OF REPRODUCTIVE AGE IN KADUNA STATE, NIGERIA

Simple item page
dc.contributor.authorAKUT, DEBORAH
dc.date.accessioned2018-09-10T09:34:32Z
dc.date.available2018-09-10T09:34:32Z
dc.date.issued2017-08
dc.descriptionA THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE DEGREE IN MICROBIOLOGY DEPARTMENT OF MICROBIOLOGY, FACULTY OF LIFE SCIENCES AHMADU BELLO UNIVERSITY, ZARIA, NIGERIAen_US
dc.description.abstractRubella (German measles) is a vaccine preventable disease caused by Rubella virus. The public health importance of rubella relates to the teratogenic effects of the virus when acquired in the early months of pregnancy. The purpose of the study was to determine the Seroprevalence and detect the presence of Rubella virus among women of reproductive age in Kaduna State, Nigeria. A total of 360 women between the ages of 15 and 45 years attending the selected health facilities were enrolled for the study and blood and throat swab specimens obtained from these women were analysed using ELISA and Nested RT-PCR techniques. The prevalence of Rubella virus IgG and IgM antibodies obtained among the 360 women examined was 343(95.3%) for Rubella IgG antibodies and 93(25.8%) for Rubella IgM antibodies. Women between the age group of 40 and 45 had the highest prevalence of 100% while women between the age group of 25 and 29 years had the lowest prevalence of 92.9% for Rubella IgG antibody. Women between the age group of 15-19 years had the highest prevalence of 31.8% while those between the ages of 20 and 24 years had the lowest of 19.6% for rubella IgM. Some of the socio-demographic and risk factors associated with rubella in this study were Senatorial district of the women, history of vaccination, joint pains (P<0.05). A positivity rate of 13% was obtained by polymerase chain reaction. Efforts should be made to make routine screening part of antenatal careen_US
dc.identifier.urihttps://kubanni.abu.edu.ng/handle/123456789/10348
dc.language.isoenen_US
dc.subjectSEROPREVALENCE,en_US
dc.subjectMOLECULAR DETECTION,en_US
dc.subjectRUBELLA VIRUS,en_US
dc.subjectWOMEN,en_US
dc.subjectREPRODUCTIVE AGE,en_US
dc.subjectKADUNA STATE,en_US
dc.subjectNIGERIAen_US
dc.titleSEROPREVALENCE AND MOLECULAR DETECTION OF RUBELLA VIRUS AMONG WOMEN OF REPRODUCTIVE AGE IN KADUNA STATE, NIGERIAen_US
dc.typeThesisen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
SEROPREVALENCE AND MOLECULAR DETECTION OF RUBELLA VIRUS AMONG WOMEN OF REPRODUCTIVE AGE IN KADUNA STATE, NIGERIA I.pdf
Size:
1.3 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.62 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
SCIENCE