ANTIOXIDANT VITAMIN STATUS OF NIGERIAN HOSPITALISED PATIENTS

No Thumbnail Available
Date
1997-11
Authors
KABARA, HASSAN T I J J A NI
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The antioxidant vitamin status (vitamin A, C and E) and albumin concentrations of 20 apparently healthy controls and 73 hospitalised patients suffering from a variety of diseased conditions., namely cardiovascular, liver, renal, diabetes and GIT disorders were assessed. Our data revealed that control subject had significantly higher Antioxidant vitamins and albumin status than Diseased subjects with the exception of females GIT Subjects who had significant1y lower vitamin E levels than their male counterparts Age and Sex had no apparent effect, on the Antioxidant status of either the healthy or diseased population. Albumin concentration in control subjects was inversely (r ::;:; - 0.416 p < 0.05) corre1ated with renal patients. The vitamin E levels of control was equally positively correlated with those for renal patients. vitamin A control was positively associated with baseline value (r = 0.470 p < 0.05). A re1ationships similar1y existed between the vitamin A levels of renal and Cardiovascular patients (r = 0.584 p < 0.05). Vitamin C levels of Cardiovascular and Diabetes renal or GIT patients (p < 0.05) were else inversely correlated. An interre1ationship was evident between the Antioxida.nt vitarnin status in Diseased condition. A1bumin was not associated with Antioxidant vitamin status in diabetes. It v is applied from present data that regular diets of hospitalised patients can not maintain acceptable Antioxidant, vitamin status in\ these patients hence dietary supplementation of Antioxidant vitamin is recommended in the management of these disorder. 1t is postu1ated from present study that the most p1ausib1e mechanism for interrelationship evident amongst the Antioxidant vitamin is a rapid uti1ization of the Vitamin as a consequence of increased free radical, produced by drugs and the pathological effects of this diseased conditions. vi
Description
A DISSERTATION PRESENTED TO THE GRADUATE SCHOOL AHHADUBELL0 UNIVERSITY, ZARIA IN PARTIAL FULFILLLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE IN BIOCHEMISTRY BY KABARA HASSAN T I J J A NI FACULTY OF SCIENCE DEPARTMENT OF BIOCHEMISTRY AHMAOU BELLO UNIVERSITY ZARIA, NIGERIA
Keywords
ANTIOXIDANT VITAMIN STATUS,, NIGERIAN,, HOSPITALISED PATIENTS.
Citation
Collections