ANTIOXIDANT VITAMIN STATUS OF NIGERIAN HOSPITALISED PATIENTS
ANTIOXIDANT VITAMIN STATUS OF NIGERIAN HOSPITALISED PATIENTS
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Date
1997-11
Authors
KABARA, HASSAN T I J J A NI
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Abstract
The antioxidant vitamin status (vitamin A, C and E) and
albumin concentrations of 20 apparently healthy controls and
73 hospitalised patients suffering from a variety of
diseased conditions., namely cardiovascular, liver, renal,
diabetes and GIT disorders were assessed. Our data revealed
that control subject had significantly higher Antioxidant
vitamins and albumin status than Diseased subjects with the
exception of females GIT Subjects who had significant1y
lower vitamin E levels than their male counterparts Age and
Sex had no apparent effect, on the Antioxidant status of
either the healthy or diseased population. Albumin
concentration in control subjects was inversely (r ::;:; - 0.416
p < 0.05) corre1ated with renal patients.
The vitamin E levels of control was equally positively
correlated with those for renal patients. vitamin A control
was positively associated with baseline value (r = 0.470 p <
0.05). A re1ationships similar1y existed between the vitamin
A levels of renal and Cardiovascular patients (r = 0.584 p <
0.05).
Vitamin C levels of Cardiovascular and Diabetes renal or GIT
patients (p < 0.05) were else inversely correlated. An
interre1ationship was evident between the Antioxida.nt
vitarnin status in Diseased condition. A1bumin was not
associated with Antioxidant vitamin status in diabetes. It
v
is applied from present data that regular diets of
hospitalised patients can not maintain acceptable
Antioxidant, vitamin status in\ these patients hence dietary
supplementation of Antioxidant vitamin is recommended in the
management of these disorder.
1t is postu1ated from present study that the most p1ausib1e
mechanism for interrelationship evident amongst the
Antioxidant vitamin is a rapid uti1ization of the Vitamin as
a consequence of increased free radical, produced by drugs
and the pathological effects of this diseased conditions.
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Description
A DISSERTATION PRESENTED TO THE GRADUATE SCHOOL
AHHADUBELL0 UNIVERSITY, ZARIA
IN PARTIAL FULFILLLMENT OF THE REQUIREMENTS
FOR THE DEGREE OF MASTER OF SCIENCE IN BIOCHEMISTRY
BY
KABARA HASSAN T I J J A NI
FACULTY OF SCIENCE
DEPARTMENT OF BIOCHEMISTRY
AHMAOU BELLO UNIVERSITY
ZARIA, NIGERIA
Keywords
ANTIOXIDANT VITAMIN STATUS,, NIGERIAN,, HOSPITALISED PATIENTS.