A New Prenylated Chalcone from the Stem-bark of Lonchocarpus sericeus Poir (Papilionaceae)
A New Prenylated Chalcone from the Stem-bark of Lonchocarpus sericeus Poir (Papilionaceae)
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Date
2013
Authors
Abdullahi, SM,
Musa, AM
Abdullahi, MI
Sani, YM
Sule, MI
Journal Title
Journal ISSN
Volume Title
Publisher
African Journal of Pharmaceutical Research and Development
Abstract
Lonchocarpus sericeus belonging to the papilionaceae family is a plant used in folk medicine for the treatment of convulsion,
backache, constipation and anorexia. 2',4'-dihydroxy-3'-(4-hydroxy-4-methyl pentenyl)-chalcone was isolated from the
chloroform soluble fraction of the methanol extract of Lonchocarpus sericeus bark using a combination of silica gel column
chromatography and gel filtration,. The structure of this compound was elucidated with the help of 1D and 2D NMR
spectroscopic analysis. This is the first report of isolation of this compound. Detailed HSQC and HMBC have been provided
for the new compound.
Description
Abdullahi SM1', Musa AM1, Abdullahi MI2, Sani YM1 and Sule MI1
1Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
2Department of Pharmaceutical Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria
Keywords
Prenylated,, Chalcone,, Stem-bark,, Lonchocarpus sericeus,, Poir (Papilionaceae),