SOME ASPECTS OF THE EPIDEMIOLOGY AND DRUG SENSITIVITY OF BOVINE TRYPANOSOMOSIS IN KAURA LOCAL GOVERNMENT AREA OF KADUNA STATE
SOME ASPECTS OF THE EPIDEMIOLOGY AND DRUG SENSITIVITY OF BOVINE TRYPANOSOMOSIS IN KAURA LOCAL GOVERNMENT AREA OF KADUNA STATE
| dc.contributor.author | DOMINIC, BAWA MAIKAJE | |
| dc.date.accessioned | 2014-09-11T08:22:21Z | |
| dc.date.available | 2014-09-11T08:22:21Z | |
| dc.date.issued | 1998-03 | |
| dc.description | A thesis in the Department of Parasitology and Entomology, Faculty of Veterinary Medicine, submitted to the Postgraduate School, Ahmadu Bello University Zaria, in partial fulfillment of the requirements for the award of the Doctor of Philosophy (Ph.D) degree in Veterinary Parasitology and Entomology. March, 1998 | en_US |
| dc.description.abstract | Outbreaks of tsetse fly infestation and bovine trypanosomosis in Kaura Local Government area (LGA) of Kaduna State, leading to high cattle mortality and mass exodus of settled Fulani pastoralists from the area were reported in the National Concord daily Newspaper of 6th November, 1990. Using the biconical and NiTse tsetse traps, Glossina palpalis palpalis and G. tachinoides were caught only along the banks of River Kajim in Kaura LGA. Stomoxys calcitrans. Haematopota spp, and Tabanus spp were detected in every part of the LGA using the same tsetse trapping equipment. Results of parasitological surveys conducted in this LGA revealed dry and rainy seasons bovine trypanosomosis prevalence rates of 17.26% and 53.04%, respectively. The antigen capture enzyme-linked immunosorbent assay (ELISA) revealed bovine typanosomosis prevalence rates of 49.40% and 63.48%, respectively during the two seasons. The principal etiologic agents of bovine trypanosomosis detected during these investigations were Trypanosoma brucei, followed by T. congolense and T. vivax and mixed infections with the three trypanosome species. Drug sensitivity tests conducted in Red Sokoto goats revealed complete sensitivity of the X, brueei isolate to diminazene diaceturate (BerenilR ) and isometamidium chloride (Samorin ), at doses of 7 mg/kg and 0.5 mg/kg body weight respectively. On the other hand, the T. congolense isolate in one of three experimentally infected goats relapsed to diminazenc at 7 mg/kg body weight three weeks post treatment. The remaining two, and three others from another group, infected with the same trypanosome isolate were cured with the 7.0 mg/kg diminazene and 0.5 mg/kg isometamidium respectively. It was concluded that there were outbreaks of bovine trypanosomosis and its vectors which could hamper cattle breeding in Kaura LGA. The seemingly efficient trapping of the bovine trypanosomosis vectors using the biconical and NiTse tsetse traps observed during this study suggests that the large scale use of this locally fabricated equipment might effectively control these biting flies in Kaura LGA. Similarly, inspite of the rampant misuse of trypanocidal drugs in this LGA, many trypanosome isolates are still apparently sensitive to the therapeutic doses of the commonly used trypanocides - diminazene diaceturate and isometamidium cloride. The chemothcrapcutic/chcinoprophylactic treatment of cattle may provide another viable option for the control of bovine trypanosomosis in Kama LGA. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/5320 | |
| dc.language.iso | en | en_US |
| dc.subject | EPIDEMIOLOGY, | en_US |
| dc.subject | DRUG SENSITIVITY, | en_US |
| dc.subject | BOVINE TRYPANOSOMOSIS, | en_US |
| dc.subject | KAURA LOCAL GOVERNMENT AREA OF KADUNA STATE | en_US |
| dc.title | SOME ASPECTS OF THE EPIDEMIOLOGY AND DRUG SENSITIVITY OF BOVINE TRYPANOSOMOSIS IN KAURA LOCAL GOVERNMENT AREA OF KADUNA STATE | en_US |
| dc.type | Thesis | en_US |