METHICILLIN RESISTANCE PROFILE OF STAPHYLOCOCCUSAUREUS ISOLATED FROM BURN WOUND PATIENTS IN SELECTED HOSPITALS IN ZARIA, NIGERIA
METHICILLIN RESISTANCE PROFILE OF STAPHYLOCOCCUSAUREUS ISOLATED FROM BURN WOUND PATIENTS IN SELECTED HOSPITALS IN ZARIA, NIGERIA
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Date
2018-06
Authors
BATURE, Muhammad
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Abstract
Antimicrobial resistance is a persistent problem where antibiotics are abused or misused. The work determined the methicillin resistance profile of Staphylococcus aureus isolated from burn wound patients in selected hospitals in Zaria, Nigeria. A total of 160 burn wound swabs were obtained from patients and inoculated on Mannitol Salt Agar (MSA) medium. Twelve (12) Staphylococcus aureusisolates were biochemically characterized. Antibiotic susceptibility testing was carried out on all the isolates by disk diffusion method. All the isolates were resistant to at least 2 out of 8 antibiotics tested. The resistancepattern of the isolates was:Cefoxitin(100%),Oxacillin(83.33%),Tetracycline(75%), Vancomycin(75%),Ciprofloxacin(66.7%),Erythromycin(66.7), Gentamicin(41.7%) andChloramphenicol(25%). The Multiple Antibiotic Resistance Index was between 0.25-1.00. Out of the 12 Staphylococcus aureus isolates 9 were methicillin resistant as detected using PBP latex agglutination test kit. It is important that hospitals should monitor Staphylococcusaureus infection in patients with burn wound so as to facilitate management and treatment of the burn wound
Description
A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA, IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE DEGREE IN MICROBIOLOGY DEPARTMENT OF MICROBIOLOGY FACULTY OF LIFE SCIENCES AHMADU BELLO UNIVERSITY, ZARIA
Keywords
METHICILLIN RESISTANCE PROFILE,, STAPHYLOCOCCUSAUREUS ISOLATED,, BURN WOUND PATIENTS,, SELECTED HOSPITALS,, ZARIA,, NIGERIA,