SERUM LIPID CHANGES IN RABBITS WITH SINGLE AND MIXED TRYPANOSOMA BRUCEI BRUCEI AND TRYPANOSOMA CONGOLENSE INFECTION.
SERUM LIPID CHANGES IN RABBITS WITH SINGLE AND MIXED TRYPANOSOMA BRUCEI BRUCEI AND TRYPANOSOMA CONGOLENSE INFECTION.
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Date
2014-11-11
Authors
SANDA, SAFIYA ASIBI
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Abstract
The packed cell volume and serum lipids of male New Zealand
rabbits with single and mixed infections of Trypanosoma brucei and
Trypanosoma congolense were investigated. In the mixed infection
group, T.brucei was the predominant parasite species and the
clinical picture tended towards that of single T.brucei infection.
Anaemia was a significant feature of the disease in all the
infected animals with PCV values significantly lower than that of
control animals. There was no significant (P>0.05) difference
between the PCV of all the infected animals. All the infections
were characterized by hypercholesterolemia, hypertriglyceridemia,
hypoalbuminemia and elevated serum free fatty acid levels which
were significantly higher (P<0.05) in all the infected groups
compared to the control group. Elevated serum total cholesterol
and triglyceride serve as predictors of coronary heart disease and
may therefore be a cause of death in the infected animals
Description
A thesis submitted to the postgraduate school, Ahmadu Bello
University in partial fulfilment of the requirements for the award
of Master of Science (M.Sc.) Biochemistry.
Department of Biochemistry
Faculty of Science
Ahmadu Bello University
Zaria, Nigeria
Keywords
SERUM,, LIPID,, RABBITS,, TRYPANOSOMA,, BRUCEI BRUCEI,, TRYPANOSOMA,, CONGOLENSE,, INFECTION.