SERUM LIPID CHANGES IN RABBITS WITH SINGLE AND MIXED TRYPANOSOMA BRUCEI BRUCEI AND TRYPANOSOMA CONGOLENSE INFECTION.

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Date
2014-11-11
Authors
SANDA, SAFIYA ASIBI
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Abstract
The packed cell volume and serum lipids of male New Zealand rabbits with single and mixed infections of Trypanosoma brucei and Trypanosoma congolense were investigated. In the mixed infection group, T.brucei was the predominant parasite species and the clinical picture tended towards that of single T.brucei infection. Anaemia was a significant feature of the disease in all the infected animals with PCV values significantly lower than that of control animals. There was no significant (P>0.05) difference between the PCV of all the infected animals. All the infections were characterized by hypercholesterolemia, hypertriglyceridemia, hypoalbuminemia and elevated serum free fatty acid levels which were significantly higher (P<0.05) in all the infected groups compared to the control group. Elevated serum total cholesterol and triglyceride serve as predictors of coronary heart disease and may therefore be a cause of death in the infected animals
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A thesis submitted to the postgraduate school, Ahmadu Bello University in partial fulfilment of the requirements for the award of Master of Science (M.Sc.) Biochemistry. Department of Biochemistry Faculty of Science Ahmadu Bello University Zaria, Nigeria
Keywords
SERUM,, LIPID,, RABBITS,, TRYPANOSOMA,, BRUCEI BRUCEI,, TRYPANOSOMA,, CONGOLENSE,, INFECTION.
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