ANALYSIS OF TRACE METALS, TOTAL LIPIDS, AND CHOLESTEROL LEVELS IN BLOOD OF AJAOKUTA STEEL WORKERS
ANALYSIS OF TRACE METALS, TOTAL LIPIDS, AND CHOLESTEROL LEVELS IN BLOOD OF AJAOKUTA STEEL WORKERS
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Date
1991
Authors
MAKUN, HUSSAINI ANTHQNY
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Abstract
Serum concentrations of total lipids, cholesterol,
copper, Iron, magnesltim and zinc were determined In
eighty-two AJaokuta Steel workers. Blood concentrations
of antimony, arsenic, bismuth, cadmium, cobalt,
lead, manganese and nickel were also determined in
the steel workers. Similar determinations were
made for twenty students of Ahmadu Bello University,
Zaria, that served as the controls.
The mean serum total lipids in the controls
(598.75 mg/l00ml) was not significantly (P/0.05)
different from the value obtained for the steel
workers (568.25 mg/100ml). Similarly, the serum
cholesterol levels in controls (206.42 mg/100ml)
did not differ significantly (P/0.05) from the levels
in the steel workers (183.82 mg/l00ml).
There were no significant (P/0.05) differences
between the serum copper concentrations In controls
(1.26 ppm) and the levels in the steel workers
(l.14. ppm). Also, there were no significant (P/0.05)
differences observed between the serum magnesium
content In controls (26.17 ppm) and the concentrations
in steel workers (26.I4.3 ppm).
At 5% level of significance serum iron levels
in controls (4. 28 ppm) did not differ significantly
from iron levels in steel workers (3.62 ppm).
However, serum zinc levels in stool workers (1.85 ppm)
were significantly (P/O.05) higher than the levels
in the controls (0.83 ppm).
Arsenic, antnmony, bismuth, cadmium, cobalt,
lead, manganese and nickel were not detected in the
blood of both the steel workers and their controls.
Except for the blood zinc concentrations which
were significantly elevated in steel-workers as
compared to levels in controls, oil other studied
parameters were within normal range. The duration, of
year of service in the industry did not have any
significant (P/0.05) effect on the concentrations of
the parameters studied. Similarly sex had no effect
on the studied parameters except for serum total l i p i ds
which was. s i g n i f i c a n t l y (P/O.O5) higher in the female
controls than in the male controls.
Description
Thesis submitted to the Postgraduate School, Ahmadu
Bello University, Zaria in partial fulfillment of
the requirements for the degree of MASTER OF SCIENCE
DEPARTMENT OF BIOCHEMISTRY
FACULTY OF SCIENCE
AHMADU BELLO UNIVERSITY
ZARIA
NIGERIA,
1991.
Keywords
ANALYSIS,, TRACE METALS,, TOTAL LIPIDS,, CHOLESTEROL,, LEVELS,, BLOOD,, AJAOKUTA,, STEEL WORKERS.