DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AND ASSOCIATED TRAITS: A STUDY OF THE COLLEGE OF NURSING AND MIDWIFERY, OBANGEDE, KOGI STATE

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dc.contributor.authorALIYU, ABDULGANIYU ADEIZA
dc.date.accessioned2017-07-24T16:07:19Z
dc.date.available2017-07-24T16:07:19Z
dc.date.issued2016-10
dc.descriptionA DISSERTATION SUBMITTED TO SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA, NIGERIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF THE DEGREE OF MASTER OF SCIENCE IN HUMAN ANATOMY DEPARTMENT OF HUMAN ANATOMY FACULTY OF MEDICINE AHMADU BELLO UNIVERSITY, ZARIA, NIGERIAen_US
dc.description.abstractIn the last five decades, genetic structure of populations are being studied in via ABO blood groups system, mtDNA and Y chromosome makers to understand history of human migration and relatedness of ethnic groups settled in close proximity. In the present study, the distribution of ABO and Rh blood groups and associated traits among various ethnic groups in Kogi State was analysed to determine the genetic composition of various ethnic groups. The study was carried out using students of Kogi State College of Nursing and Midwifery, Obangede. Participants for the study included 1,863 students of the college (1,427 females and 436 males) aged 16-40 years. The study is both retrospective and prospective. Records of admitted students into the college spanning 11 years (2002–2013) consecutively were retrospectively and prospectively collected from the various record units of the College. ABO, Rh blood group and Hb-electrophoresis tests were carried out on a white porcelain tile using blood grouping antisera and Hb-electrophoresis machine. From the 1,863 records reviewed for the ABO blood group, the phenotypic frequencies were highest for ABO*O (965, 51.80%) followed by ABO*B (404, 21.70%). The frequencies for ABO*A was observed as (379, 20.30%), whereas the frequency of ABO*AB group was observed to be lowest (115, 9.00%). It was observed that ABO*O > ABO*B > ABO*A > ABO*AB for each sex. The same pattern was observed for all the ethnic groups with a slight deviation in Bassa and Nupe where group A>B. The distribution of Rh antigen shows that Rh D positive was the highest with 1,755 (94.20%) while Rh D Negative was the lowest with 108 (5.8%). The genotypic frequency for haemoglobin was discovered to be highest for AA 1,095(58.50%) followed by AS 768 (41.00%) SS was observed to be comparatively very low 9(0.50%). The present study reveals association of ABO with malaria, hepatitis and level of academic performance of the subjects. There is also a weak association with birth order, BMI, height and weight. xvi The result from this study is in line with the observed trend in other studies in Nigeria and also suggest that the ABO blood group disease association may affect more of metabolic than infectious diseases.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/9109
dc.language.isoenen_US
dc.subjectDISTRIBUTION,en_US
dc.subjectABO,en_US
dc.subjectRH (D) BLOOD GROUPS,en_US
dc.subjectASSOCIATED TRAITS,en_US
dc.subjectSTUDY,en_US
dc.subjectCOLLEGE OF NURSING AND MIDWIFERY,en_US
dc.subjectOBANGEDE,en_US
dc.subjectKOGI STATEen_US
dc.titleDISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AND ASSOCIATED TRAITS: A STUDY OF THE COLLEGE OF NURSING AND MIDWIFERY, OBANGEDE, KOGI STATEen_US
dc.typeThesisen_US
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