EXPERIMENTAL CANINE SURGICAL EXPLORATIONS UNDER SUBCUTANEOUSLY (KETAMINE) IN DUCED ANAESTHESIA WITH CHLORPROMAZINE PREMEDICATION IN DOGS.
EXPERIMENTAL CANINE SURGICAL EXPLORATIONS UNDER SUBCUTANEOUSLY (KETAMINE) IN DUCED ANAESTHESIA WITH CHLORPROMAZINE PREMEDICATION IN DOGS.
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Date
2007-08
Authors
ADEOLA, BABALOLA SAMUEL
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Abstract
This study was undertaken to explore the possibility or otherwise of conducting invasive
(gastrotomy) and non invasive (intergumentry (H-plasty)) surgical procedures following
subcutaneous administration of ketamine hydrochloride in dogs. Twenty four (24)
Nigerian indigenous dogs were used for the study, 10 underwent integumentry (H-plasty)
procedures, while 10 underwent gastrotomy procedures. They were premedicated with
chlorpromazine at a dose of 3.0 mg/kg and atropine at a dose of 0.03 mg/kg, employing
the intravenous and intramuscular routes respectively. Ketamine was administered
subcutaneously at an initial dose of 10 mg/kg and the dogs evaluated for surgical
anaesthesia using standard assessment protocol and thereafter subjecting them to the
above mentioned surgical procedures. During surgery, basic anaesthetic parameters were
monitored and recorded.
A concurrent observational study was carried out on four other Nigerian indigenous
dogs; they were premedicated with chlorpromazine at a dose of 3.0 mg/kg, atropine at a
dose of 0.03 mg/kg intravenously and intramuscularly respectively and
anaesthetized with thiopental intravenously at an initial dose of 10 mg/kg. Being the
standard anaesthetic protocol used at the Ahmadu Bello University Veterinary
Teaching Hospital, Small Animal Surgery Unit.
At the end of the study, 10 mg/kg single administration and 14.5 mg/kg total multiple
administration of ketamine were judged adequate for integumentry and gastrotomy
procedures respectively.
Description
A THESIS SUBMITTED TO THE
POSTGRADUATE SCHOOL,
AHMADU BELLO UNIVERSITY, ZARIA
NIGERIA
IN PARTIAL FULFILMENT FOR THE AWARD OF
MASTER OF SCIENCE (MSc) IN VETERINARY
ANAESTHESIA
DEPARTMENT OF VETERINARY SURGERY AND
MEDICINE, FACULTY OF VETERINARY MIDICINE.
AHMADU BELLO UNIVERSITY, ZARIA.
NIGERIA.
Keywords
EXPERIMENTAL CANINE,, SURGICAL EXPLORATIONS,, UNDER SUBCUTANEOUSLY (KETAMINE),, IN DUCED ANAESTHESIA, CHLORPROMAZINE,, PREMEDICATION IN DOGS