RADIOISOTOPIC DETERMINATION OF SERUM FOLIC ACID, RED CELL FOLATE AND SERUM VITAMIN B1 2 CONCENTRATION OF BLOOD DONORS IN ZARIA
RADIOISOTOPIC DETERMINATION OF SERUM FOLIC ACID, RED CELL FOLATE AND SERUM VITAMIN B1 2 CONCENTRATION OF BLOOD DONORS IN ZARIA
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Date
1982-11
Authors
MALLAM, SIMON PESCO
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Abstract
A simple model for calculating the concentration
of two important vitamins ( folic acid and vitamin B12)
i n human blood donors using the radio assay technique
has been described . An analisies of t his model has
shown that where is need to e stability optimal working
concentrations of re agents difference from those
recommended by the supplied of the radio a say kits ,
depending the age of the kit, if high assay
sensitivity is to be achieve.
It has also been shown the difference of
Amer sham give very wide delay spread concentrations of serum
f o l i c acid (SFA)»red c e l l f o l a t e (RCF) and serum
vitamin B12 (SB1 2 ) even with the symptom-free d o n o r s.
These concentration showed very poor correlation
w i t h those obtained by the microbiological using
the microorganism L. case is for the , due of
probablly to difference in the response of the two a say.
"The mean SPA, RCF and SB12 levels for the symptom
r e e blood donors in Zaria were found tc be 6.2 + 2.2
μ g / l , 318 ± 7 5 u g / l , 383 ± 27 n g / 1 respectivelly by the
technique. The normal reference ranges for t h e s e donors
were found to be 1 - 37 (μg/1, 98 - 1035 μg/1 and
99 - 1482 n g / l for SFA, RCF and S B 1 2 respectively
Description
A Thesis submitted to the Post-graduate
School in partial fulfillment of the requirement
for the degree of Master of Science, Nuclear
Physics .
Department of Physics
Ahmadu Bello University Zaria,Nigeria
November, 1982.
Keywords
RADIOISOTOPIC,, DETERMINATION,, SERUM,, FOLIC,ACID,, RED CELL,, FOLATE,, SERUM,, VITAMIN B1 2,, CONCENTRATION,, BLOOD DONORS,, ZARIA.