SEROEPIDEMIOLOGY OF HERPES SIMPLEX VIRUS TY PE 1 (HSV-1) IN PLATEAU STATE OF NIGERIA.
SEROEPIDEMIOLOGY OF HERPES SIMPLEX VIRUS TY PE 1 (HSV-1) IN PLATEAU STATE OF NIGERIA.
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Date
1985-09
Authors
MIRI, GRACE RINMEGIT SAMSON
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Abstract
ABSTRACT.
Six hundred and forty eight serum samples collectedfrom individuals in the nine health zones of Plateau State were analysed for the presence of Herpes simplex virus type 1 (HSV-l) antibodies using the enzyme - linked
immunosorbent assay (ELISA). Out of the 648 serum samples analysed, 446 were positive giving a prevalence rate of 69% in the population. Immunity to the virus varied with socioeconomic status. While seropositivity was 76% among individuals of the low socioeconomic class, it was 58% among individuals of the high socioeconomic class (P< 0.025). Whereas 80% of children from the low class had antibodies during the first 10 years of life, only 22% from the high class were seropositive. This difference was
highly significant (P< 0.025). However, after 21 years of age, there was not much difference between the two classes. IgM prevalence decreased with an increase
in age. IgG prevalence also decreased from birth to the first year of life, after which there was an increase in prevalence with increase in age. Immunity
to HSV-l in males and females was similar in all age groups except for the 11 - 20 years age group where prevalence was higher in females (P < 0.05).
Description
A Thesis submitted to the Postgraduate School,
Ahmadu Bello University, Zaria, Nigeria, in
Partial Fulfillment of the Requirements for
the Degree of: MASTER OF SCIENCE
Department of Microbiology, Faculty of Science, `Ahmadu Bello University,
Zaria, NIGERIA
Keywords
SEROEPIDEMIOLOGY,, HERPES,, SIMPLEX VIRUS,, TY PE 1 (HSV-1),, PLATEAU STATE, NIGERIA.