Isolation of Lupeol from the Stem-bark of Lonchocarpus sericeus (Papilionaceae)
Isolation of Lupeol from the Stem-bark of Lonchocarpus sericeus (Papilionaceae)
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Date
2013-01
Authors
Abdullahi, S.M
Musa, A.M
Abdullahi, M.I.
Sule, M.I
Sani, Y.M.
Journal Title
Journal ISSN
Volume Title
Publisher
An International Publisher for Academic and Scientific Resources
Abstract
Lupeol, a pentacyclic triterpenoid, was isolated from the chloroform soluble fraction of a methanol extract of
the stem-bark of Lonchocarpus sericeus, a plant variously used in ethnomedicine to stimulate appetite, treat constipation,
backache and convulsion. Its isolation was carried out by a combination of column chromatography and preparative Thin
Layer Chromatography. The structure was determined by analysis of its IR, 'H NMR, l3C NMR, and 2D NMR spectral
data, as well as comparison with reported data. This is the first report of isolation of lupeol from the stem-bark of this
species.
Description
Keywords
Isolation,, Lupeol,, Stem-bark,, Lonchocarpus sericeus,, (Papilionaceae)