DETECTION OF Mycobacterium bovis ANTIBODIES USING THE LATERAL-FLOW TECHNIQUE IN SMALL RUMINANTS IN KADUNA METROPOLIS, NIGERIA

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dc.contributor.authorHARUNA, Esther Godiya
dc.date.accessioned2014-02-21T11:03:42Z
dc.date.available2014-02-21T11:03:42Z
dc.date.issued2013-02
dc.descriptionA THESIS SUBMITTED TO SCHOOL OF POSTGRADUATE STUDIES, IN PARTIAL FULFILLMENT OF THE REQUIRMENTS FOR THE AWARD OF THE DEGREE OF MASTER OF SCIENCE IN VETERINARY PUBLIC HEALTH AND PREVENTIVE MEDICINE DEPARTMENT OF VETERINARY PUBLIC HEALTH AND PREVENTIVE MEDICINE AHMADU BELLO UNIVERSITY ZARIA, NIGERIA FEBRUARY, 2013en_US
dc.description.abstractThe study was designed to determine the prevalence of Mycobacterium bovis (M. bovis) antibodies in sheep and goats in slaughter houses and livestock markets, and the risk of infection and level of awareness of animal handlers/owners to bovine tuberculosis within Kaduna metropolis. A total of 1010 sera samples from small ruminants, consisting of 498 sheep and 512 goats were collected at random from 4 abattoirs during slaughter and from livestock markets within the metropolis. The Anigen® Rapid Bovine TB Antibody Test which is specific for M. bovis was used to determine the presence of bovine tuberculosis antibodies in the serum samples. Structured questionnaires were distributed to animal handlers/owners after being pilot tested and adjusted. The results showed that out of the total 1010 sera samples taken, 137 (13.56%). tested positive to bovine tuberculosis. Species specific prevalence rates of 10.84% (54/498) for sheep and 16.41% (84/512) for goat were found. There was significant association between detection of M. bovis antibodies and species sampled, with goats having a significantly higher prevalence than sheep (P<0.05; χ² = 7.153, P= 0.0075). Females of both species had sero-prevalence of 14.98% (89/594) while males had 11.54% (48/416). The sero-prevalence amongst age groups was 12%, 15%, 7% and 14% for 1-12months, 13-24months, 25-36months and ≥36months respectively. There was significance occurrence of reactors to bovine tuberculosis amongst the age group greater than 24 months (P< 0.05). Sero-prevalence of 13.36% (68/509) and 13.77% (69/501) for slaughter houses and livestock markets respectively was recorded. Sixty-five percent of the respondents were aware of the disease tuberculosis (TB), 41.9% were aware of bovine TB while 39.7% were aware that bovine TB is zoonotic. Level of education was found to be associated with the degree of awareness of bovine tuberculosis as zoonoses among the respondents (P = 0.0001). Out of the 72.5% respondents that keep livestock, 55% of them do so in close proximity with the humans and 52% have a preference for small ruminant as source of meat. The detection of Mycobacterium bovis infection in apparently healthy small ruminants is of public health significant, considering their close proximity to humans. There is therefore the need to educate the populace on zoonotic implication of bovine tuberculosis and the relevant authorities should put in place control measures against the disease.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/2321
dc.language.isoenen_US
dc.subjectDETECTIONen_US
dc.subjectMycobacterium bovisen_US
dc.subjectANTIBODIESen_US
dc.subjectLATERAL-FLOWen_US
dc.subjectTECHNIQUEen_US
dc.subjectSMALL RUMINANTSen_US
dc.subjectKADUNA METROPOLISen_US
dc.subjectNIGERIAen_US
dc.titleDETECTION OF Mycobacterium bovis ANTIBODIES USING THE LATERAL-FLOW TECHNIQUE IN SMALL RUMINANTS IN KADUNA METROPOLIS, NIGERIAen_US
dc.typeThesisen_US
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