SYNTHESIS, APPLICATION AND ANTIMICROBIAL PROPERTIES OF AZO DYES DERIVED FROM 2-AMINOTHIOPHENE AND CONVENTIONAL AMINES AS DIAZO COMPONENTS
SYNTHESIS, APPLICATION AND ANTIMICROBIAL PROPERTIES OF AZO DYES DERIVED FROM 2-AMINOTHIOPHENE AND CONVENTIONAL AMINES AS DIAZO COMPONENTS
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Date
2017-07
Authors
AGHO, OSAZEE BRIGHT
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Abstract
Twelve different monoazo heterocyclic disperse and acid dyes of low molecular weight derived from 2-aminothiophene and conventional amines as diazo components were successfully synthesized. The identities of the synthesized dyes and intermediates were investigated using spectroscopic analysis such as Uv-visible spectrometry, Fourier Transform Infrared Spectrometry and Gas Chromatography Mass Spectrometry. The 2-aminothiophene intermediates and heterocyclic disperse dyes were synthesized using the Gewald‟s method and the molar mass of the synthesized intermediates were between 257-285 g/mol while that of the synthesized dyes were between 305-614 g/mol. All the synthesized dyes absorbed within the visible region of the electromagnetic spectrum but the heterocyclic disperse dyes synthesized from the 2-aminothiophene intermediates were more bathochromic than those of the conventional amines dyes. The heterocyclic disperse dyes gave good exhaustion ranging from 60 % to 78 % on polyester fabric while the acid dyes on chrome tanned leather gave an excellent exhaustion of 80 % to 87 %. The dyes gave mostly brown, deep purple and orange shades and exhibited good to excellent fastness properties on the dyed substrates. For wash fastness, it was between 5 (excellent) and 3 (good), while for light fastness it was between 6 (good) and 4 (moderate). The antimicrobial screening of the synthesized dyes against six (6) different microorganisms were assessed using the Agar Well diffusion method and the results showed zones of inhibition ranging from 3-34 mm, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal/Fungicidal Concentration (MBC/MFC) values as low as 12.5 mg/ml, which indicate that the dyes can be effective against infectious diseases which these microorganisms can cause.
Description
A DISSERTATION SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE (M.Sc.) IN COLOUR CHEMISTRY AND TECHNOLOGY DEPARTMENT OF POLYMER AND TEXTILE SCIENCE, FACULTY OF PHYSICAL SCIENCES,AHMADU BELLO UNIVERSITY, ZARIA, NIGERIA
Keywords
SYNTHESIS,, APPLICATION,, ANTIMICROBIAL,, PROPERTIES,, AZO,, DYES,, DERIVED,, 2-AMINOTHIOPHENE,, CONVENTIONAL,, DIAZO,, COMPONENTS,