SCREENING FOR VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS AMONG PATIENTS ATTENDING HOSPITALS IN SAMARU, ZARIA- NIGERIA

Simple item page
dc.contributor.authorSALAU, ABUBAKAR OMEIZA
dc.date.accessioned2017-11-20T09:21:53Z
dc.date.available2017-11-20T09:21:53Z
dc.date.issued2014-10
dc.descriptionA THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE DEGREE (M.Sc.) IN MICROBIOLOGY DEPARTMENT OF MICROBIOLOGY, FACULTY OF SCIENCE, AHMADU BELLO UNIVERSITY, ZARIA NIGERIAen_US
dc.description.abstractThis study investigated the susceptibility of S.aureus to Vancomycin and other antibiotics used for the treatment of patients attending Hospitals in Samaru. A total of 400 samples comprising urine (250), wound (75) and pus swab (75) were analysed. The clinical samples yielded a prevalence of 71 (17.80%) of S.aureus by conventional method and confirmed with microgen analytical test kit.Antimicrobial susceptibility of the isolates was tested by disc diffusion method. There was a higher prevalence of S.aureus from in-patient than out-patient. The highest frequency of S.aureus was found in age group (0-9 years). The S. aureus strains showed a 100.00% susceptibility to vancomycin and gentamicin but showed resistance to ampicillin (90.10%), chloramphenicol (12.70%), erythromycin (28.20%), cefoxitin (33.80%), tetracycline(14.10%), and linezolid (9.90%). In this study, the MIC of Ampicillin againstS.aureus ranged from 3.91 μg/ml to 62.50μg/ml, Tetracycline ranged 15.63-31.25μg/ml, Cefoxitin ranged from 7.81μg/ml to 62.50μg/ml, Chloramphenicol ranged from 3.91-31.25μg/ml and Erythromycin ranged from 3.91-15.63μg/ml. While the MBC of Ampicillin against S.aureus ranged from 7.81-125.00μg/ml, Tetracycline ranged from 31.25-62.50μg/ml, Cefoxitin ranged from 15.63-125.00μg/ml, Chloramphenicol ranged from 7.81-62.50μg/ml and Erythromycin ranged from 7.81-31.25μg/ml. The study showed that a significant percentage of the isolates were resistant to different antibiotics used suggesting the need for control strategies to avoid dissemination of resistant strains.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/9476
dc.language.isoenen_US
dc.subjectSCREENING,en_US
dc.subjectVANCOMYCIN RESISTANT,en_US
dc.subjectSTAPHYLOCOCCUS AUREUS,en_US
dc.subjectPATIENTS ATTENDING HOSPITALS,en_US
dc.subjectSAMARU,en_US
dc.subjectZARIA- NIGERIA,en_US
dc.titleSCREENING FOR VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS AMONG PATIENTS ATTENDING HOSPITALS IN SAMARU, ZARIA- NIGERIAen_US
dc.typeThesisen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
SCREENING FOR VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS AMONG PATIENTS ATTENDING HOSPITALS IN SAMARU, ZARIA- NIGERIA..pdf
Size:
1.8 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.62 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
SCIENCE