CONCENTRATION OF VITAMIN C, VITAMIN E AND IRON IN APPARENTLY HEALTHY PREGNANT WOMEN AND THE CORD BLOOD AT PATURATION
CONCENTRATION OF VITAMIN C, VITAMIN E AND IRON IN APPARENTLY HEALTHY PREGNANT WOMEN AND THE CORD BLOOD AT PATURATION
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Date
1998-11
Authors
GEORGE, ELEANOR ONYIMA
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Abstract
The effects of maternal age, parity and Hb concentration
on the antioxidant vitamins (Vitamins E and C) and Iron
nutriture of 50 women of reproductive age (control) and 60
Nigerian parturient mothers and the cord levels were assessed.
The mean serum Vitamin C and E concentrations for 50 non
pregenant Nigerian women was 0.96±0.lOmg/dl and
1.65±0.07mg/dl, respectively. Apparently, age and parity had
no effect (P>0.05) on the antioxidant status of the women. Age
correlated positively with parity (r=0.7l) but inversely (r=-
0.85) (P<0.05) with the serum Vitamin C concentrations.
Haemoglobin was positively associated (P<0.05) with PCV
(r=0.72^ and serum Vitamin C concentration (r=0.31) for these
subjects while PCV correlated with both Vitamin C (r«0.30) and
Vitamin E (r=0.39) concentrations for the subjects.
The mean maternal serum Vitamin C, Vitamin E and Iron
concentration of the parturient mothers studied were
0 . 58 + 0 . llmg/dl, 1. 55±0 . 08mg/dl and 114 . 3±59 . 90/ug/dl,
respectively. The corresponding fetal values were
0.77±0.20mg/dl, 0 . 27±0 .19mg/dl and 167 . 9±62 . 20/ug/dl,
respectively. Parturient mothers aged 20-24 years had
significantly lower maternal Hb, PCV and serum Vitamin E
(P<0.C5) compared to other age groups. Anaemic parturient
mothers (Hb<10.Og/dl) also had significantly lower (P<0.05),
PCV, Vitamin C and Iron compared to non-anaemic subjects
(Hb>ll.Og/dl) Parity had no apparent effect (P>0.05) on either
the maternal or fetal antioxidant status. Maternal Hb was
positively associated (P<0.05) with (PCV) (r=0.89), Maternal
serum Vitamin C (r=0.330) and Iron (r=0.45), while maternal
PCV correlated (P<0.05) with maternal Vitamin C (r=0.30) and
Vitamin E (r-0.397) . Fetal Hb, on the contrary, was not
associated with either Fetal Vitamin C (r=0.10) or Vitamin E
(r=0.035) levels but was associated with fetal Iron.
Data from the present study suggests that there are no
metabolic relationships (P>0.05) between antioxidant Vitamin
E and C concentration in non pregnant Nigerian women or
between maternal and cord values in parturient women
Description
A THESIS SUBMITTED TO THE POST-GRADUATE SCHOOL,
DEPARTMENT OF BIOCHEMISTRY,
AHMADU BELLO UNIVERSITY, ZARIA,
IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR
THE AWARD OF THE MASTER OF SCIENCE DEGREE IN BIOCHEMISTRY
Keywords
CONCENTRATION,, VITAMIN C,, VITAMIN E,, IRON,, APPARENTLY,, HEALTHY,, PREGNANT,, WOMEN,, CORD,, BLOOD,, PATURATION.