OCCURRENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILES OF DERMATOPHILUS CONGOLENSIS ISOLATES FROM SLAUGHTERED CATTLE IN ABUJA, NIGERIA

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dc.contributor.authorOPUTEH, Kingsley
dc.date.accessioned2019-01-30T08:45:46Z
dc.date.available2019-01-30T08:45:46Z
dc.date.issued2018-08
dc.descriptionA DISSERTATION SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF THE DEGREE OF MASTER OF SCIENCE IN VETERINARY MICROBIOLOGYen_US
dc.description.abstractABSTRACT Antibiotic resistance has long been recognized as a major problem in the treatment of bacterial infections including dermatophilosis. This study was carried out to determine the occurrence and antimicrobial susceptibility profiles of Dermatophilus congolensisisolates obtained from slaughtered cattle at the Karu abattoir in the Federal Capital Territory Abuja, and to determine the rate of isolation of the bacterium during the wet and dry periods respectively. One hundred and thirty five (135) skin scabs were obtained from animals suspected to be infected with Dermatophilus congolensisbased on observed clinical signs. Ninety two (68.1%) of these suspected cases occurred during the wet period (August to October) while 43 (31.9%) were in the dry period. The scab samples were subjected to both direct examination with methylene blue staining and culture for isolation on blood agar to determine and confirm the presence of D. congolensis. The Dermatophilusisolates obtained were tested against eight commonly used antibiotics namely; Augmentin, Cloxacillin, Gentamicin, Cefuroxime, Ceftriaxone, Ceftazidine, Ofloxacin and Erythromycin. Following direct examination, all 135 skin scab samples were found to be positive for D. congolensis with characteristic branching filamentous rods, however only 53 (39.3%) yielded typical D. congolensis isolates via culture and isolation.Out of the 53 isolates tested to eight commonly used antibiotics, the majority (94.3%) of the isolates were sensitive to Ofloxacin, 42 (79.2%) to Ceftazidine, 26 (49.1%) and 21 (39.6%) to Gentamicin and Ceftriaxone respectively. On the other hand, all the isolates(100%) were resistant to Cefuroxime, Erythromycin, Cloxacillin and Augmentin at concentrations up to 250μg/ml. The study established the presence of D. congolensis among slaughtered cattle in the region.There were no statistical association in the rate of D. congolensis isolation between the breeds encountered or the sex of the animals examinedwith the rate of detection of the organism. However the highest caseof the infection was recorded during the rainy period.In conclusion there is a need for clinicians to carry out antimicrobial susceptibility testing on isolates of D.congolensis to vii determine the most effective antibiotics against specific isolates for theen_US
dc.identifier.urihttp://hdl.handle.net/123456789/11115
dc.language.isoenen_US
dc.subjectOCCURRENCE,en_US
dc.subjectANTIMICROBIAL SUSCEPTIBILITY,en_US
dc.subjectPROFILES,en_US
dc.subjectDERMATOPHILUS CONGOLENSIS,en_US
dc.subjectISOLATES,en_US
dc.subjectSLAUGHTERED CATTLE,en_US
dc.subjectABUJA, NIGERIAen_US
dc.titleOCCURRENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILES OF DERMATOPHILUS CONGOLENSIS ISOLATES FROM SLAUGHTERED CATTLE IN ABUJA, NIGERIAen_US
dc.typeThesisen_US
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