EFFECTS OF EXPERIMENTAL TRYPANOSOMA VIVAX INFECTION ON THE OESTROUS CYCLE OF MATURE YANKASA EWES

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Date
1989-12
Authors
ADENOWO, THOMAS KEHIMDE OLUWAFEMI
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Abstract
Twelve mature Yankasa sheep (6 infected and 6 control ewes) were used to investigate the effects of experimental Trypanosoma vivax infection on selected reproductive organs and on oestrous cycle parameters. Daily rectal temperatures and weekly body weights were taken, and blood samples for haematology were also collected twice a week from all the animals before and after the infection. Prior to infection, oestrus was synchronised using progestagen sponges, following which animals were observed for oestrus signs twice daily (A.M. arid P.M.) using a vasectomised ram. Heat observations were carried out daily and plasma for progesterone determination collected every other day for 2 cycles to assess oestrous cycle parameters prior to infection and subsequently till end of the experimental period. Undulating parasitaemia, hyperthermia and anaemia were observed in infected ewes following T. vivax infection. Three types of abnormal oestrus occurred based on progesterone profiles: 2 infected ewes showed silent oestrus, 2 others exhibited temporary anoestrus while the last 2 showed complete anoestrus. These oestrus anomalies were associated with various degrees of pathological observations such as mononuclear (mostly lymphocytes and macrophages) cellular infiltration and necrosis of the anterior pituitary gland, and hyalinization of the ovary with no evidence of follicular development. These results confirm that T. vivax infection can adversely affect reproduction through interference with ovarian activity and other reproductive organs of Yankasa ewes.
Description
A THESIS SUBMITTED TO THE POSTGRADUATE AOSCFH IMEATNDHCUE E ,RB EEDQLEULPIOAR RETUMMNEEINNVTTES R OSFFIO TRVY E TTIHENER IDPNEAARGRYRT EIPEA ALR OAFFS ULTIMATUM OSILTSLOECLGRHMY OE ONOTLF AND ENTOMOLOGY, AHMADU BELLO, UNIVERSITY, ZARIA KADUNA STATE, NIGERIA DECEMBER, 1989.
Keywords
EFFECTS,, EXPERIMENTAL,, TRYPANOSOMA,, VIVAX,, INFECTION,, OESTROUS CYCLE,, YANKASA EWES,, MATURE.
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