ANTIBIOGRAM OF UROPATHOGENIC BACTERIA ISOLATED FROM PATIENTS IN SOME HOSPITALS IN BIRNIN KUDU, JIGAWA STATE, NIGER

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dc.contributor.authorKACHALLAH, Mohammed
dc.date.accessioned2018-09-05T08:04:11Z
dc.date.available2018-09-05T08:04:11Z
dc.date.issued2016-08
dc.descriptionDEPARTMENT OF PHARMACEUTICS AND PHARMACEUTICAL MICROBIOLOGYen_US
dc.description.abstractUrinary tract infection (UTI) is a common infection of human being and if untreated could lead to serious complications. This study was conducted to investigate the antibiotic susceptibility pattern of uropathogens from patients in two hospitals in Birnin kudu, Jigawa State, Nigeria. In this study, the antibiotic resistance profile and the plasmid profile of some multi-antibiotic resistant bacteria isolated from urine samples of patients from Birnin kudu community in North-west, Nigeria were analysed. Rapid diagnostic kit systems were used in identification of the isolated bacteria and agar disc diffusion technique was used for the determination of antibiotic susceptibility profiles of the isolated bacteria. Presence of β- lactamase was determined using standardized β-lactamase identification sticks while acridine orange was used for curing of multidrug resistant isolates. The cultures of some multi- antibiotic resistant isolates irreversibly lost their antibiotic resistance with acridine orange treatment, which suggests that the resistant genes could be harboured in the plasmids. The result showed that 94.3% of the isolates were resistant to Ampicillin, Amoxycillin-clavulanic acid (71.5%), Ceftriaxone (35.4%), Cefuroxime (57.3), Cotrimoxazole (73.1%), Nitrofurantoin (24.6%), Chloranphenicol (36.9), Doxycycline (58.0%), Ciprofloxacin (60.0%) and Gentamicin (61.2%). Out of 36 isolates tested for presence of β- lactamse, 66.1% possessed β- lactamases. Plasmid profile studies revealed the presence of plasmid of size range 5184.8kb – 5673.9bp. .en_US
dc.identifier.urihttp://hdl.handle.net/123456789/10231
dc.language.isoenen_US
dc.subjectANTIBIOGRAM,en_US
dc.subjectUROPATHOGENIC BACTERIA ISOLATED,en_US
dc.subjectPATIENTS,en_US
dc.subjectHOSPITALS,en_US
dc.subjectBIRNIN KUDU,en_US
dc.subjectJIGAWA STATE,en_US
dc.subjectNIGER,en_US
dc.titleANTIBIOGRAM OF UROPATHOGENIC BACTERIA ISOLATED FROM PATIENTS IN SOME HOSPITALS IN BIRNIN KUDU, JIGAWA STATE, NIGERen_US
dc.typeThesisen_US
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