SEROLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS (PPR) IN SHEEP, GOATS AND CAMELS IN SOKOTO STATE, NIGERIA

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dc.contributor.authorBELLO, MUHAMMAD BASHIR
dc.date.accessioned2014-02-07T12:11:48Z
dc.date.available2014-02-07T12:11:48Z
dc.date.issued2013-04
dc.descriptionBEING A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF A DEGREE OF MASTER OF SCIENCE IN VETERINARY MICROBIOLOGYen_US
dc.description.abstractPeste des petits ruminant (PPR) is a highly contagious viral disease of small ruminants that is regarded as one of the most important militating factors against small ruminant production in Nigeria. Despite its endemicity in Sokoto State, scanty or no report of PPR exist in the State. Therefore, this study was aimed at determining the current serological status of the disease in sheep, goats and camels in Sokoto State, Nigeria. A total of 433 serum samples obtained from small ruminants (sheep and goats) in six randomly selected Local Government Areas (Tambuwal, Goronyo, Wurno, Kware, Bodinga and Sokoto South LGAs) in the State were examined for the presence of PPR antibodies using a monoclonal antibody-based competitive enzyme linked immunosorbent assay (c-ELISA). The sera were collected only from those small ruminants of not less than six months old and with no history of vaccination against PPR. The overall seroprevalence of PPR in small ruminants was 45.50% (197/433) while that of camel was 18.25% (25/137). Chi square test of independence at 95% confidence interval revealed a statistically significant difference in the seroprevalence rates among the LGAs sampled: Goronyo (56.72%), Tambuwal (59.10%), Bodinga (33.71%), Kware (53.24%), Wurno (18.60%) and Sokoto South (68.75%). Furthermore, sheep (52.41%) had a statistically greater seroprevalence rate than the goats (40.24%) sampled in this study (p=0.015). In addition, small ruminants aged 13- 24 months had a significantly greater prevalence of PPR antibodies than other age groups considered in this study (p=0.015). However, While there was statistically significant difference in the seroprevalence rates of various breeds of goats considered in this study (p= 0.0179), in the sheep breeds, the difference was not statistically significant. The detection of PPR virus antibodies in small ruminants from all the LGAs sampled suggests ix the wide distribution of the virus in the study area. In addition, the detection of PPR virus antibodies in the camel population sampled suggests that they are equally susceptible to PPR virus like sheep and goats. It is therefore recommended that PPR control programmes such as vaccination with PPR homologous vaccine should be intensified in the study area. Further studies on the isolation and molecular characterization of the virus in the study area are also recommendayionen_US
dc.identifier.urihttp://hdl.handle.net/123456789/727
dc.language.isoenen_US
dc.subjectSEROLOGICALen_US
dc.subjectSTUDIESen_US
dc.subjectPESTEen_US
dc.subjectDESen_US
dc.subjectPETITSen_US
dc.subjectRUMINANTSen_US
dc.subjectSHEEP,en_US
dc.subjectGOATSen_US
dc.subjectGOATSen_US
dc.subjectCAMELSen_US
dc.subjectSOKOTOen_US
dc.subjectSTATEen_US
dc.subjectNIGERIAen_US
dc.titleSEROLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS (PPR) IN SHEEP, GOATS AND CAMELS IN SOKOTO STATE, NIGERIAen_US
dc.typeThesisen_US
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