SEROLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS (PPR) IN SHEEP, GOATS AND CAMELS IN SOKOTO STATE, NIGERIA
SEROLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS (PPR) IN SHEEP, GOATS AND CAMELS IN SOKOTO STATE, NIGERIA
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Date
2013-04
Authors
BELLO, MUHAMMAD BASHIR
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Abstract
Peste des petits ruminant (PPR) is a highly contagious viral disease of small ruminants that
is regarded as one of the most important militating factors against small ruminant
production in Nigeria. Despite its endemicity in Sokoto State, scanty or no report of PPR
exist in the State. Therefore, this study was aimed at determining the current serological
status of the disease in sheep, goats and camels in Sokoto State, Nigeria. A total of 433
serum samples obtained from small ruminants (sheep and goats) in six randomly selected
Local Government Areas (Tambuwal, Goronyo, Wurno, Kware, Bodinga and Sokoto South
LGAs) in the State were examined for the presence of PPR antibodies using a monoclonal
antibody-based competitive enzyme linked immunosorbent assay (c-ELISA). The sera
were collected only from those small ruminants of not less than six months old and with no
history of vaccination against PPR. The overall seroprevalence of PPR in small ruminants
was 45.50% (197/433) while that of camel was 18.25% (25/137). Chi square test of
independence at 95% confidence interval revealed a statistically significant difference in
the seroprevalence rates among the LGAs sampled: Goronyo (56.72%), Tambuwal
(59.10%), Bodinga (33.71%), Kware (53.24%), Wurno (18.60%) and Sokoto South
(68.75%). Furthermore, sheep (52.41%) had a statistically greater seroprevalence rate than
the goats (40.24%) sampled in this study (p=0.015). In addition, small ruminants aged 13-
24 months had a significantly greater prevalence of PPR antibodies than other age groups
considered in this study (p=0.015). However, While there was statistically significant
difference in the seroprevalence rates of various breeds of goats considered in this study
(p= 0.0179), in the sheep breeds, the difference was not statistically significant. The
detection of PPR virus antibodies in small ruminants from all the LGAs sampled suggests
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the wide distribution of the virus in the study area. In addition, the detection of PPR virus
antibodies in the camel population sampled suggests that they are equally susceptible to
PPR virus like sheep and goats. It is therefore recommended that PPR control programmes
such as vaccination with PPR homologous vaccine should be intensified in the study area.
Further studies on the isolation and molecular characterization of the virus in the study area
are also recommendayion
Description
BEING A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE
STUDIES, AHMADU BELLO UNIVERSITY, ZARIA
IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF
A DEGREE OF MASTER OF SCIENCE IN VETERINARY MICROBIOLOGY
Keywords
SEROLOGICAL, STUDIES, PESTE, DES, PETITS, RUMINANTS, SHEEP,, GOATS, GOATS, CAMELS, SOKOTO, STATE, NIGERIA