MINERAL STATUS OF APPARENTLY HEALTHY NORMAL PREGNANT WOMEN AND THEIR NEONATES AT PARTUBITION
MINERAL STATUS OF APPARENTLY HEALTHY NORMAL PREGNANT WOMEN AND THEIR NEONATES AT PARTUBITION
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Date
1992-05
Authors
DANLADI, ICCE
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Abstract
The mineral s t a t u s , hematologic and
socioeconomic s t a t u s of 55 a p p a r e n t l y h e a l t hy
prurient mothers resident in Northern Nigeria and
t h e i r neonates were evaluated. The mineral status
of 20 apparently healthy non-pregnant women of
c h i l d - b e a r i n g age who served as the c o n t r ol
subjects were simultaneously determined. Their
mineral status was evaluated by measuring the serum
concentrations of 5 trace and 2 macro-elements
namely Fe,Cu,Zn,Mn,Cr and Ca Mg respectively while
Hb and PCV served as the hematological parameters
evaluated. Base-line data from the present study
indicate that with the exception of Ca and Cu, the
control subjects had adequate mineral s t a t u s/
Although the parturient women had lower (p<0.05) Hb
and PCV indices than the control subjects, it is
evident from the study that mineral levels are in
creased following pregnancy. The mean serum Fe, Cu
and Ca concentrations of the control subjects were
82.00 ± 23.30, 6.67 + 4.88 ug\100ml and 8.62 ± 2.75
mg\100ml respectively while the maternal mean serum
levels for the same elements were 149.18 ± 54.87,
125.47 ± 113.20 JJg/100ml.
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and 11.90 + 3.30 mg/1OOml respectively. Fetal
Fe, Cu and Ca levels were also 194.73 + 104.67,
110.32 ± 86.69 ug/1OOml and 12.3 + 3.98mg\100ml respecively.
Regression analysis revealed significant (P<
0.05) positive association between Cu and Zn(r=o.713),
and Zn and Mn(r=0.522) in the control
Subjects. Age and Mg, Cu and Mn and PCV and Mg bore a
converse correlation in the maternal serum. With the
Exception of Fe which bore a negative correlation, the
maternal - fetal mineral interrelationships were positive
for each element suggesting that maternal circulation is
the main fetal source of the elements. Maternal age,
Parity, hematologic and socioeconomic status had no
significant (P>0.05) effect on the fetal mineral status.
The various interrelationships evident between the
numerous parameters in the present study are discussed
Description
A THESIS SUBMITTED TO THE POSTGRADUATE SCHOOL,
DEPARTMENT OF BIOCHEMISTRY, AHMADU BELLO
UNIVERSITY, ZARIA IN PARTIAL FULFILLMENT OF THE
REQUIREMENTS FOR THE AWARD OF THE MASTER OF
SCIENCE DEGREE IN BIOCHEMISTRY
MAY, 1992
Keywords
MINERAL,, STATUS,, APPARENTLY,, HEALTHY,, NORMAL,, PREGNANT,, PREGNANT,, WOMEN,, NEONATES,, PARTUBITION